Recombinant Human Cytokeratin 17
Produktgrößen
20 µg
£528,00
32-4072-20UG
Über dieses Produkt
- SKU:
- 32-4072
- Zusätzliche Namen:
- Keratin 17||PCHC1||39.1||CK-17||K17||PC2||PC||cytokeratin-17; Keratin 17 Epitope S1||Keratin 17 Epitope S2||Keratin 17 Epitope S4||Keratin; Type I Cytoskeletal 1||keratin-17||Cytokeratin-17||Keratin-17.
- Weitere Details:
- Source : Escherichia Coli. KRT17 Human Recombinant produced in E.Coli is a single; non-glycosylated polypeptide chain containing 455 amino acids (1-432 a.a) and having a molecular mass of 50.5kDa.KRT17 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Cytokeratin 17 also known as KRT17 is a type I cytokeratin. KRT17 is found in nail beds; hair follicles; sebaceous glands; and other epidermal appendages. Mutations in KRT17 lead to Jackson-Lawler type pachyonychia congenita and steatocystoma multiplex. KRT17 takes part in the formation and maintenance of a variety of skin appendages; particularly in determining shape and orientation of hair. KRT17 also modulates the function of TNF-alpha in the precise context of hair cycling. Moreover; KRT17 regulates protein synthesis and epithelial cell growth all through binding to the adapter protein SFN and by stimulating Akt/mTOR pathway.
- Aufreinigung:
- "Greater than 90% as determined by SDS-PAGE."
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please avoid freeze thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Datenblatt des Herstellers:1.jpg