IER3 Recombinant Protein
Produktgrößen
10 µg
£528,00
32-4006-10UG
Über dieses Produkt
- SKU:
- 32-4006
- Zusätzliche Namen:
- immediate early response 3||DIF-2||DIF2||GLY96||IEX-1; IEX-1L||IEX1||PRG1||Protein DIF-2||Immediate early protein GLY96||PACAP-responsive gene 1 protein||Differentiation-dependent gene 2 protein||IER3.
- Weitere Details:
- Source : Escherichia Coli. IER3 Human Recombinant produced in E.Coli is a single; non-glycosylated polypeptide chain containing 105 amino acids (1-82 a.a.) and having a molecular mass of 11.4kDa.IER3 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Immediate Early Response 3 (IER3) functions in the protection of cells from Fas- or tumor necrosis factor type alpha-induced apoptosis. IER3 has a role in the ERK signaling pathway by inhibiting the dephosphorylation of ERK by phosphatase PP2A-PPP2R5C holoenzyme. In addition; IER3 serves as an ERK downstream effector mediating survival. As a member of the NUPR1/RELB/IER3 survival pathway; IER3 provides pancreatic ductal adenocarcinoma with significant resistance to cell stress; such as starvation or gemcitabine treatment.
- Aufreinigung:
- Greater than 85.0% as determined by SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Datenblatt des Herstellers:1.jpg