HAX1 Recombinant Protein
Produktgrößen
10 µg
£528,00
32-3937-10UG
Über dieses Produkt
- SKU:
- 32-3937
- Zusätzliche Namen:
- HCLS1-associated protein X-1||HS1-associating protein X-1||HS1-binding protein 1||HAX-1||HSP1BP-1||HAX1||HS1BP1.
- Weitere Details:
- Source : E.coli. HAX1 Human Recombinant produced in E. coli is a single polypeptide chain containing 299 amino acids (1-279) and having a molecular mass of 33.7kDa. HAX1 is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. HAX1 associates with hematopoietic cell-specific Lyn substrate 1; which is a substrate of Src family tyrosine kinases. HAX1 also interacts with the product of the polycystic kidney disease 2 gene; mutations in which are associated with autosomal-dominant polycystic kidney disease; and with the F-actin-binding protein; cortactin. It was earlier thought HAX1 is mainly localized to the mitochondria; however; recent studies indicate it to be localized in the cell body. Mutations in the HAX1 gene result in autosomal recessive severe congenital neutropenia; aka Kostmann disease.
- Aufreinigung:
- Greater than 80% as determined by SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Datenblatt des Herstellers:1.jpg