FETUB Recombinant Protein
Produktgrößen
10 µg
£528,00
32-3828-10UG
Über dieses Produkt
- SKU:
- 32-3828
- Zusätzliche Namen:
- Fetuin-B||16G2||Fetuin-like protein IRL685||Gugu||FETUB||IRL685.
- Weitere Details:
- Source : HEK 293. Fetuin-B Human Recombinant produced in HEK cells is a single; glycosylated; polypeptide chain containing a total of 377 amino acids; having a molecular mass of 41.8kDa (calculated) though it migrates at approximately 55kDa on SDS PAGE; the Fetuin-B is also composed of a 4 a.a N-terminal linker and fused to a 6 a.a His tag at C-Terminus.The Human FETUB is purified by proprietary chromatographic techniques. Fetuin-B (FETUB) belongs to the fetuin family; part of the cystatin superfamily proteins and comprised of 2 cystatin domains. Fetuin-B is found in a secreted form in the serum; it is expressed in the liver; tongue and placenta. FETUB regulates osteogenesis by inhibition effect on mineralization. Fetuins are implicated in a number of various functions; including osteogenesis and bone resorption; regulation of the insulin and hepatocyte growth factor receptors; and response to systemic inflammation. FETUB also has a role in oocyte maturation. Fetuin-B is essential in preventing premature zona pellucida hardening before fertilization; probably by inhibiting the protease activity of ASTL; which is a protease that mediates the cleavage of ZP2 and triggers zona pellucida hardening.
- Aufreinigung:
- Greater than 90.0% as determined by SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store lyophilized protein at -20[o]C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4[o]C for a limited period of time; it does not show any change after two weeks at 4[o]C.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Datenblatt des Herstellers:1.jpg