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ESM1 Recombinant Protein

Produktgrößen
20 µg
£528,00
32-3766-20UG
Über dieses Produkt
SKU:
32-3766
Zusätzliche Namen:
Endothelial cell-specific molecule 1||ESM-1||ESM1||endocan.
Weitere Details:
Source : Escherichia Coli. ESM1 Human Recombinant produced in E.Coli is a single; non-glycosylated polypeptide chain containing 188 amino acids (20-184 a.a.) and having a molecular mass of 20.5kDa.ESM1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Endothelial cell-specific molecule 1 (ESM1) is a proteoglycan secreted by endothelial cells (mostly in the human lung and kidney tissues) and its mRNA expression is regulated by inflammatory cytokines. ESM1 has potent implications in lung endothelial cell-leukocyte interactions. In addition; ESM1 expression is detected in various epithelia and in adipocytes. ESM1 is involved in angiogenesis and it also promotes angiogenic sprouting. ESM1 expression is upregulated by TNF alpha; IL1 beta; or lipopolysaccharide and downregulated by IFN gamma. Genetically engineered cells overexpressing ESM1 induce tumor formation; implying that ESM1 might be involved in the pathophysiology of tumor growth in vivo.
Aufreinigung:
Greater than 90.0% as determined by SDS-PAGE.
Versandbedingungen:
Blue Ice
Lagerbedingungen:
Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Hersteller:
Abeomics
Typ:
Proteins, Peptides, Small Molecules & Other Biomolecules
  • Datenblatt des Herstellers:1.jpg