GNAQ Recombinant Protein
Produktgrößen
20 µg
£528,00
32-3717-20UG
Über dieses Produkt
- SKU:
- 32-3717
- Zusätzliche Namen:
- Guanine Nucleotide Binding Protein (G Protein)||Q Polypeptide; Guanine Nucleotide-Binding Protein Alpha-Q||CMC1||SWS||GAQ||Guanine Nucleotide-Binding Protein G(Q) Subunit Alpha||G-ALPHA-Q||Guanine nucleotide-binding protein G(q) subunit alpha.
- Weitere Details:
- Source : Escherichia Coli. GNAQ Human Recombinant produced in E.Coli is a single; non-glycosylated polypeptide chain containing 382 amino acids (1-359 a.a) and having a molecular mass of 44.5kDa. GNAQ is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. GNAQ; also known as Guanine nucleotide-binding protein belong to the G-alpha family. Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in a variety of transmembrane signaling systems. GNAQ regulates B-cell selection and survival and is essential in order to prevent B-cell-dependent autoimmunity. GNAQ also regulates chemotaxis of BM-derived neutrophils and dendritic cells; in vitro. GNAQ is an alpha subunit in the Gq class; couples a seven-transmembrane domain receptor to activation of phospolipase C-beta. Mutations at this locus have been connected with problems in platelet activation and aggregation. A related pseudogene to GNAQ exists on chromosome 2.
- Aufreinigung:
- Greater than 90.0% as determined by SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Datenblatt des Herstellers:1.jpg