DEDD Recombinant Protein
Produktgrößen
10 µg
£528,00
32-3668-10UG
Über dieses Produkt
- SKU:
- 32-3668
- Zusätzliche Namen:
- CASP8IP1||DEDD1||DEFT||FLDED1||KE05||DEDPro1||Death effector domain-containing testicular molecule.
- Weitere Details:
- Source : Escherichia Coli. DEDD Human Recombinant produced in E.Coli is a single; non-glycosylated polypeptide chain containing 338 amino acids (1-318a.a) and having a molecular mass of 38.9kDa. DEDD is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Death effector domain-containing protein (DEDD) is a cytoplasmic protein. The cell death activity of DEDD relates to its nuclear localization. DEDD translocates to the nucleus during CD95-mediated apoptosis; there it localizes to nucleoli-like structures; activates caspase-6 and particularly inhibits RNA polymerase I-dependent transcription. DEDD is usually expressed in a variety of tissues; and found in the highest levels in the testis. Overexpression of DEDD was shown to induce weak apoptosis.
- Aufreinigung:
- Greater than 85.0% as determined by SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Datenblatt des Herstellers:1.jpg