CTHRC1 HEK Recombinant Protein
Produktgrößen
10 µg
£528,00
32-3634-10UG
Über dieses Produkt
- SKU:
- 32-3634
- Zusätzliche Namen:
- Collagen Triple Helix Repeat Containing 1||Protein NMTC1||CTHRC1.
- Weitere Details:
- Source : HEK 293. CTHRC1 Human Recombinant produced in HEK cells is a single; glycosylated; polypeptide chain (Ser31-Lys243) containing a total of 219 amino acids; having a calculated molecular mass of 23.9kDa and fused to a 6 aa His tag at C-Terminus. Collagen triple helix repeat-containing protein 1 (CTHRC1) functions as a negative regulator of collagen matrix deposition. CTHRC1 is a secreted 28kDa protein which is glycosylated and highly conserved from lower chordates to mammals. CTHRC1 is highly connected with calcified tissues and cartilaginous matrix; but not with endothelial cells. CTHRC1 is detected qualitatively in plasma of healthy human subjects. CTHRC1 plasma levels are also significantly elevated during pregnancy; in diabetes; in inflammatory and infectious conditions; in subjects with acute myeloid leukemia but not in subjects with solid cancers. The hormonal functions of CTHRC1 include regulation of lipid storage and cellular glycogen levels with potentially far-reaching implications for cell metabolism and physiology. CTHRC1 gene deletion leads to fatty liver (steatosis) formation in mice while others exhibited inactivation of the CTHRC1 gene also results in low bone mass.
- Aufreinigung:
- Greater than 95.0% as determined by SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store lyophilized protein at -20[o]C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4[o]C for a limited period of time; it does not show any change after two weeks at 4[o]C.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Datenblatt des Herstellers:1.jpg