COMP HEK Recombinant Protein
Produktgrößen
10 µg
£528,00
32-3574-10UG
Über dieses Produkt
- SKU:
- 32-3574
- Zusätzliche Namen:
- Cartilage Oligomeric Matrix Protein (pseudoachondroplasia epiphyseal dysplasia 1 multiple)||MED||THBS5||TSP5||EDM1||PSACH||EPD1||Thrombospondin-5.
- Weitere Details:
- Source : HEK293 COMP HEK Protein is a 82.4 kDa protein containing 750 aa fused to a 13 aa N-Terminal FLAG-tag. COMP is a non-collagenous glycoprotein and is belongs to the thrombospondin family of extracellular proteins. COMP is a calcium-binding protein of high molecular weight (>500kDa) found in the extracellular matrix of articular; nasal and tracheal cartilage. COMP is not only cartilage-derived but is common in other tissues; such as synovium and tendon. Intact COMP is pentameric; with five equal subunits and the carboxy-terminal globular domain of native COMP binds to collagens I; II; and IX. COMP molecules are vital for conserving the properties and integrity of collagen network. Moreover COMP has a storage and delivery function for hydrophobic cellsignaling molecules such as vitamin D. Mutations of the COMP gene cause Pseudoachondroplasia and some forms of multiple epiphyseal dysplasia which implicates that it is vital that COMP develops and functions normally.
- Aufreinigung:
- of the protein.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store lyophilized COMP HEK Human at -20[o]C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted COMP HEK can be stored at 4[o]C for a limited period of time; it does not show any change after two weeks at 4[o]C.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Datenblatt des Herstellers:1.jpg