CENPA Recombinant Protein
Produktgrößen
20 µg
£528,00
32-3503-20UG
Über dieses Produkt
- SKU:
- 32-3503
- Zusätzliche Namen:
- Histone H3-like centromeric protein A||Centromere protein A||CENP-A||Centromere autoantigen A||CENPA.
- Weitere Details:
- Source : Sf9 insect cells. CENPA Human Recombinant produced in SF9 is a glycosylated; polypeptide chain having a molecular mass of 17;015 Dalton. CENPA is expressed with a -6x His tag and purified by proprietary chromatographic techniques. Centromere proteins are a group of proteins which form and/or mediate the function of centromeres; the central structures of chromosomes to which spindle fibers/microtubuli attach and pull the chromosomes apart in cell division. Currently; 9 centromere proteins are known and designated CENPA to CENP-I. Most of the centromere proteins are targets of autoantibodies; the anti-centromere antibodies.CENPA is another important centromeric autoantigen in addition to CENPB: it has a molecular weight of approx. 20 kDa and is incorporated into centromeric chromatin due to its histone-like properties. CENPA antibodies are an important marker for correct diagnosis of Scleroderma / CREST syndrome in CENPB-autoantibody negative patients.
- Aufreinigung:
- Greater than 90% as determined by SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. Avoid multiple freeze-thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Datenblatt des Herstellers:1.jpg