CD95 His Recombinant Protein
Produktgrößen
20 µg
£528,00
32-3483-20UG
Über dieses Produkt
- SKU:
- 32-3483
- Zusätzliche Namen:
- CD95||CD-95||Tumor necrosis factor receptor superfamily member 6||FASLG receptor||Apoptosis-mediating surface antigen FAS||Apo-1 antigen||CD95 antigen||FAS||APT1||FAS1||TNFRSF6||APO-1||FASTM||ALPS1A.
- Weitere Details:
- Source : Escherichia Coli. Recombinant FAS antigen/ CD95 purified from E. coli is a single non-glycosilated polypeptide chain containing amino acids 157-320 of Fas antigen (base pairs 713-1190 of cDNA sequence). The recombinant CD95 is fused to C-terminal 6-histidine amino acids.The FAS antigen is purified by proprietary chromatographic techniques. FAS / CD95 is a 36kDa transmembrane type I receptor; which belongs to the NF/NGF receptor super-family. It is a potent inducer of apoptosis in cells of the immune system upon interaction with its natural ligand; CD95L. Although the CD95/CD95L system could play a role in tumor regression; tumor cells seem to down-regulate CD95 expression as a mechanism of resistance to CD95L-induced killing by T lymphocytes and NK cells. The Fas antigen is expressed on the surface of various cell types; including activated T and B lymphocytes and T lymphoblastoid cell line. CD95 is also expressed in a broad panel of non-transformed cells outside the immune system.
- Aufreinigung:
- Greater than 95% as determined by:(a) Analysis by RP-HPLC.(b) Analysis by SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- CD95 although stable at 10[o]C for 5 days; should be stored below -18[o]C.Please prevent freeze-thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Datenblatt des Herstellers:1.jpg