CD59 Recombinant Protein
Produktgrößen
10 µg
£528,00
32-3476-10UG
Über dieses Produkt
- SKU:
- 32-3476
- Zusätzliche Namen:
- CD59 Molecule Complement Regulatory Protein||CD59 Antigen P18-20||CD59 Glycoprotein||Surface Anitgen Recognized By Monoclonal Antibody 16.3A5||Membrane Attack Complex (MAC) Inhibition Factor||Lymphocytic Antigen CD59/MEM43||Human Leukocyte Antigen MI
- Weitere Details:
- Source : Escherichia Coli. CD59 Human Recombinant produced in E.coli is a single; non-glycosylated polypeptide chain containing 100 amino acids (26-102) and having a molecular mass of 11.3kDa.CD59 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. CD59 is a cell surface glycoprotein which regulates complement-mediated cell lysis; and it is involved in lymphocyte signal transduction. CD59 is an effective inhibitor of the complement membrane attack complex; whereby it binds complement C8 and/or C9 during the compilation of this complex; thus inhibiting the incorporation of multiple copies of C9 into the complex; which is essential for osmolytic pore formation. In addition; CD59 has a role in signal transduction pathways in the activation of T cells. CD59 gene mutations cause CD59 deficiency; a disease resulting in hemolytic anemia and thrombosis; and which causes cerebral infarction.
- Aufreinigung:
- Greater than 85% as determined by SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Datenblatt des Herstellers:1.jpg