CD33 Recombinant Protein
Produktgrößen
20 µg
£528,00
32-3467-20UG
Über dieses Produkt
- SKU:
- 32-3467
- Zusätzliche Namen:
- CD33Molecule||CD33Antigen (Gp67)||Sialic Acid Binding Ig-Like Lectin 3||Sialic Acid-Binding Ig-Like Lectin 3||SIGLEC3||gp67||SIGLEC-3; Myeloid Cell Surface AntigenCD33||p67||Siglec-3||CD33Antigen.
- Weitere Details:
- Source : Escherichia Coli. CD33 Human Recombinant produced in E.Coli is a single; non-glycosylated polypeptide chain containing 265 amino acids (18-259 a.a) and having a molecular mass of 29.1kDa.CD33 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. CD33 is putative adhesion molecule of myelomonocytic-derived cells which mediates sialic-acid dependent binding to cells. CD33 prefers to bind to alpha-2;6-linked sialic acid. The sialic acid recognition site is masked by cis interactions with sialic acids on the same cell surface. In the immune response; CD33 perform as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatases through their SH2 domains which block signal transduction through dephosphorylation of signaling molecules. In addition; CD33 induces apoptosis in acute myeloid leukemia.
- Aufreinigung:
- "Greater than 90% as determined by SDS-PAGE."
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please avoid freeze thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Datenblatt des Herstellers:1.jpg