CCM2 Recombinant Protein
Produktgrößen
10 µg
£528,00
32-3429-10UG
Über dieses Produkt
- SKU:
- 32-3429
- Zusätzliche Namen:
- Cerebral Cavernous Malformation 2||C7orf22||malcavernin||Cerebral Cavernous Malformations 2 Protein||Chromosome 7 Open Reading Frame 22||OSM||MGC4067.
- Weitere Details:
- Source : Escherichia Coli. CCM2 Human Recombinant produced in E.Coli is a single; non-glycosylated polypeptide chain containing 311 amino acids (66-353 a.a) and having a molecular mass of 34.3kDa.CCM2 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Cerebral Cavernous Malformation 2; also known as CCM2 is a piece of the CCM signaling pathway which is a vital regulator of heart and vessel formation as well as integrity. CCM2 performs through the stabilization of endothelial cell junctions. In addition; CCM2 functions as a scaffold protein for MAP2K3-MAP3K3 signaling. CCM2 plays a key role in the modulation of MAP3K3-dependent p38 activation induced by hyperosmotic shock. Mutations in CCM2 result in cerebral cavernous malformations. Multiple transcript variants encoding dissimilar isoforms have been discovered for CCM2.
- Aufreinigung:
- "Greater than 90.0% as determined by SDS-PAGE."
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please avoid freeze thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Datenblatt des Herstellers:1.jpg