CALB1 Recombinant Protein
Produktgrößen
50 µg
£528,00
32-3398-50UG
Über dieses Produkt
- SKU:
- 32-3398
- Zusätzliche Namen:
- Calbindin||Vitamin D-dependent calcium-binding protein||avian-type||Calbindin D28||D-28K||CALB1||CAB27||CALB||calbindin 1 28kDa.
- Weitere Details:
- Source : Escherichia Coli. CALB1 Human Recombinant produced in E.Coli is a single; non-glycosylated; polypeptide chain containing 261 amino acids (1-261 a.a.) and having a molecular mass of 30kDa.The CALB1 is purified by proprietary chromatographic techniques. Calbindin 1 (CALB1) is a calcium binding protein that is a member of the troponin C superfamily. CALB1 plays a vital role in calcium regulation (including calcium transport and uptake; calcification of bone and teeth) and calcium associated signaling in neurons and transiently in embryological development. CALB1 also has a role in protecting neurons from apoptotic cell death. CALB1 buffers cytosolic calcium and may stimulate a membrane Ca2+-ATPase and a 3';5'-cyclic nucleotide phosphodiesterase. The biological function of CALB1 seems to be tied to the redox state of its five cysteine residues.CALB1 has 4 active calcium-binding domains; and 2 modified domains that seemingly have lost their calcium-binding ability. CALB1 is expressed in neural tissues. In the brain; the CALB1 synthesis is independent of vitamin-D-derived hormones. Disregulation of the CALB1 is associated with epilepsy; amyotrophic lateral sclerosis; Huntington's disease. The neurons in brains of Huntington disease patients are calbindin-depleted.
- Aufreinigung:
- Greater than 95.0% as determined by SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Datenblatt des Herstellers:1.jpg