CADM1 Recombinant Protein
Produktgrößen
10 µg
£528,00
32-3397-10UG
Über dieses Produkt
- SKU:
- 32-3397
- Zusätzliche Namen:
- Cell Adhesion Molecule 1||Tumor Suppressor In Lung Cancer 1||IGSF4||Spermatogenic Immunoglobulin Superfamily||Immunoglobulin Superfamily; Member 4||Immunoglobulin Superfamily Member 4||Synaptic Cell Adhesion Molecule; Nectin-Like Protein 2||Nectin-Li
- Weitere Details:
- Source : Escherichia Coli. CADM1 Human Recombinant produced in E.Coli is a single; non-glycosylated polypeptide chain containing 353 amino acids (45-374 a.a) and having a molecular mass of 39.4 kDa. CADM1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Cell Adhesion Molecule 1; also known as CADM1 belongs to the nectin family. CADM1 mediates homophilic cell-cell adhesion in a Ca2+-independent manner as well as mediating heterophilic cell-cell adhesion with CADM3 and PVRL3 in a Ca2+-independent manner. Furthermore; CADM1 perform as a tumor suppressor in non-small-cell lung cancer; NSCLC; cells. The interaction with CRTAM promotes natural killer (NK) cell cytotoxicity & interferon-gamma secretion by CD8+ cells in vitro over and above NK cell-mediated rejection of tumors expressing CADM3 in vivo.
- Aufreinigung:
- Greater than 85.0% as determined by SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Datenblatt des Herstellers:1.jpg