BMF Recombinant Protein
Produktgrößen
20 µg
£528,00
32-3341-20UG
Über dieses Produkt
- SKU:
- 32-3341
- Zusätzliche Namen:
- Bcl-2-modifying factor||FLJ00065||BMF.
- Weitere Details:
- Source : Escherichia Coli. Bcl2 modifying factor Human Recombinant produced in E.Coli is a single; non-glycosylated; polypeptide chain containing 144 amino acids (1-129 a.a.) and having a molecular mass of 15.6 kDa.The Bcl2 modifying factor is fused to 15 amino acid His Tag at Nterminus and purified by proprietary chromatographic techniques. Bcl2 modifying factor; is a member of the Bcl2 protein family of apoptosis mediators. Bcl2 modifying factor is widely expressed in many tissues. Bcl2 modifying factor contains a single Bcl2 homology domain 3 (BH3); and binds Bcl2 proteins and functions as an apoptotic activator. Also; Bcl2 modifying factor is important for histone deacetylase (HDAC) inhibitors which alters the balance between acetylation and deacetylation; significantly increasing histone acetylation; while strongly inducing apoptosis in a variety of cancer cell types. Bcl2 modifying factor supports Bim in regulating cell death processes in response to many stimuli. A synergistic role for bim and Bcl2 modifying factor in an apoptotic pathway leading to the clearance of Neisseria gonorrhoeae -infected cells.
- Aufreinigung:
- Greater than 90.0% as determined by SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Bcl2 modifying factor although stable 4[o]C for 4 weeks; should be stored desiccated below -18[o]C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Datenblatt des Herstellers:1.jpg