BIRC7 Recombinant Protein
Produktgrößen
20 µg
£528,00
32-3336-20UG
Über dieses Produkt
- SKU:
- 32-3336
- Zusätzliche Namen:
- Baculoviral IAP repeat-containing protein 7||KIAP||MLIAP||RNF50||ML-IAP||LIVIN||Kidney inhibitor of apoptosis protein||Melanoma inhibitor of apoptosis protein||RING finger protein 50||BIRC7.
- Weitere Details:
- Source : Escherichia Coli. BIRC7 Human Recombinant fused to N-terminal His-Tag produced in E.Coli is a single; non-glycosylated polypeptide chain containing 318 amino acids and having a molecular mass of 34 kDa. BIRC7 is a part of the inhibitor of apoptosis protein (IAP) family and contains a single copy of a baculovirus IAP repeat (BIR) as well as a RING-type zinc finger domain. The BIR domain is necessary for inhibitory activity & cooperates with caspases; while the RING finger domain sometimes increases anti-apoptotic activity but doesn't inhibit apoptosis by itself. 2 transcript variants encoding diverse isoforms have been found for this gene. The 2 isoforms have dissimilar antiapoptotic characteristics; with isoform a protecting cells from apoptosis induced by staurosporine and isoform b defending cells from apoptosis induced by etoposide. BIRC7 has direct contact with several caspases together with caspase-3; caspase-7; & caspase -9. BIRC7 inhibits the activation of caspase-9 induced by Apaf-1; cytochrome c; and dATP.
- Aufreinigung:
- Greater than 90.0% as determined by(a) Analysis by RP-HPLC.(b) Analysis by SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- BIRC7 although stable 4[o]C for 4 weeks; should be stored desiccated below -18[o]C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Datenblatt des Herstellers:1.jpg