BEND6 Recombinant Protein
Produktgrößen
20 µg
£528,00
32-3324-20UG
Über dieses Produkt
- SKU:
- 32-3324
- Zusätzliche Namen:
- BEN Domain Containing 6||C6orf65||Chromosome 6 Open Reading Frame 65||bA203B9.1||BEN Domain-Containing Protein 6||BEND6.
- Weitere Details:
- Source : Escherichia Coli. BEND6 Human Recombinant produced in E.Coli is a single; non-glycosylated polypeptide chain containing 302 amino acids (1-279 a.a) and having a molecular mass of 33.6kDa.BEND6 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. BEN domain-containing protein 6 (BEND6) is a neural BEN-solo factor which shares many functional attributes with Drosophila Insensitive; a co-repressor for the Drosophila CSL factor. The BEND6 protein binds the mammalian CSL protein CBF1 and antagonizes Notch-dependent target activation. Furthermore; its association with Notch- and CBF1-regulated enhancers is stimulated by CBF1 and antagonized by activated Notch. In utero electroporation experiments demonstrated that ectopic BEND6 impeded Notch-mediated self-renewal of neocortical neural stem cells and promoted neurogenesis.
- Aufreinigung:
- Greater than 90.0% as determined by SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Datenblatt des Herstellers:1.jpg