ATPIF1 Recombinant Protein
Produktgrößen
20 µg
£528,00
32-3265-20UG
Über dieses Produkt
- SKU:
- 32-3265
- Zusätzliche Namen:
- ATPase inhibitor mitochondrial||Inhibitor of F(1)F(o)-ATPase||IF(1)||IF1||ATPIF1||ATPI||IP||ATPIP.
- Weitere Details:
- Source : Escherichia Coli. ATPIF1 Human Recombinant produced in E.Coli is a single; non-glycosylated polypeptide chain containing 106 amino acids (26-106 a.a) and having a molecular mass of 12.2kDa.ATPIF1 is fused to a 25 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. ATPase inhibitory factor 1 (ATPIF1) attaches to the C-terminal region of a beta subunit of the F1-ATPase at low pH values and; through interference of the beta and gamma subunit interaction; ATPIF1 controls the activity of the F1 (the hydrophilic catalytic core); F0 (the membrane embedded protein channel) ATPase. ATPIF1 overexpression in a number of human carcinomas additionally reinforces its participation in oncogenesis and offers insight into the transformed metabolism of cancer cells; including the reprogramming of energy metabolism in relation to glycolysis. Endogenous F1F(o)-ATPase inhibitor curbing ATP depletion when the mitochondrial membrane potential drops below a threshold and the F1F(o)-ATP synthase begins hydrolyzing ATP to pump protons out of the mitochondrial matrix.
- Aufreinigung:
- Greater than 95.0% as determined by SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Datenblatt des Herstellers:1.jpg