AHSP Recombinant Protein
Produktgrößen
50 µg
£528,00
32-3171-50UG
Über dieses Produkt
- SKU:
- 32-3171
- Zusätzliche Namen:
- Alpha-hemoglobin-stabilizing protein||Erythroid-associated factor||Erythroid differentiation-related factor||AHSP||EDRF||ERAF.
- Weitere Details:
- Source : Escherichia Coli. AHSP Human Recombinant produced in E.Coli is a single; non-glycosylated; polypeptide chain containing 102 amino acids (1-102 a.a.) and having a molecular mass of 11.8kDa.The AHSP is purified by proprietary chromatographic techniques. Alpha-hemoglobin stabilizing protein (AHSP) is an erythroid-specific protein that acts as a chaperone to prevent the aggregation of A-hemoglobin during normal erythroid cell development. AHSP specifically protects free A-hemoglobin from precipitation in live cells and in solution. AHSP is expected to modulate pathological states of alpha-hemoglobin excess such as beta-thalassemia. Furthermore; AHSP promotes alpha globin chain stability in human erythropoiesis. In addition; the AHSP stabilizes the alpha-Hb chain; thus avoiding its precipitation and its ability to generate ROS; which is implicated in cell death. AHSP is expressed in blood and bone marrow. AHSP subunit is a monomer; it forms a heterodimer with free alpha-hemoglobin. On the other hand; AHSP does not bind beta-hemoglobin nor alpha2beta2 hemoglobin A. AHSP is downregulated in TSEs (transmissible spongiform encephalopathies).
- Aufreinigung:
- Greater than 95.0% as determined by SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Datenblatt des Herstellers:1.jpg