PKAkt1/PKBa Recombinant Protein
Produktgrößen
20 µg
£1255,00
32-3086-20UG
Über dieses Produkt
- SKU:
- 32-3086
- Zusätzliche Namen:
- RAC-alpha serine/threonine-protein kinase||EC 2.7.11.1||RAC-PK-alpha||Protein kinase B||PKB||C-AKT||AKT1||AKT||RAC||PRKBA||MGC99656||RAC-ALPHA.
- Weitere Details:
- Source : Sf9 insect cells. PKAkt1 is a glycosilated polypeptide having a molecular mass of 59.1 kDa; fused with a polyhistidine tag at N-terminus (to facilitate removal of Akt1 kinase from the reaction mixture).Inactive enzyme; suitable for negative control experiments or for phosphorylation as a substrate.Recombinant Protein Kinase B is purified by proprietary chromatographic techniques. Akt1; also known as 'Akt' or protein kinaseB (PKB) is an important molecule in mammaliancellular signaling.In humans; there are three genes in the 'Akt family': Akt1; Akt2; and Akt3. These enzymesare members of the serine/threonine-specific protein kinasefamily (EC2.7.11.1).Akt1 is involved in cellular survival pathways; by inhibiting apoptoticprocesses. Akt1 is also able to induce protein synthesispathways; and is therefore a key signaling protein in the cellular pathways that lead to skeletal muscle hypertrophy; and general tissue growth. Since it can block apoptosis; and thereby promote cell survival; Akt1 has been implicated as a major factor in many types of cancer. Akt (now also called Akt1) was originally identified as the oncogenein the transforming retrovirus; AKT8.
- Aufreinigung:
- Greater than 90% as determined by SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. Avoid multiple freeze-thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Datenblatt des Herstellers:1.jpg