p16-INK4a-TAT Recombinant Protein
Produktgrößen
25 µg
£528,00
32-3067-25UG
Über dieses Produkt
- SKU:
- 32-3067
- Zusätzliche Namen:
- Cyclin-dependent kinase 4 inhibitor A||CDK4I||p16-INK4||p16-INK4a||p16INK4A||CDKN-2A||CDKN2||Multiple tumor suppressor 1||MTS1||CMM2||MLM||TP16||p16(INK4)||p19.
- Weitere Details:
- Source : Escherichia Coli. p16-INK4a Human Recombinant is a single; non-glycosylated; polypeptide chain produced in E.coli; containing a total of 168 amino acids; which includes the 156 residues of full-length p16-INK4a and a 13-residue C-terminal TAT peptide (GGYGRKKRRQRRR); having a total Mw of 18kDa. p16-INK4a is purified by proprietary chromatographic techniques. Cyclin-dependent kinase inhibitors (CDKIs) are proteins that bind to and inhibit the activity of CDKs. Two major classes of CDK inhibitors have been identified. The p16 family (p15; p16; p18 and p19) binds to and inhibits the activities of CDK4 and CDK6. The p21 family (p21; p27; p28 and p57) can bind to broad range of CDK-cyclin complexes and inhibit their activities. CDKIs are capable of suppressing growth; and several lines of evidence strongly suggest that at least some CDKIs may be tumor suppressor proteins.
- Aufreinigung:
- Greater than 95.0% as determined by:(a) Analysis by RP-HPLC.(b) Analysis by SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Lyophilized p16-INK4a although stable at room temperature for 3 weeks; should be stored desiccated below -18[o]C. Upon reconstitution p16-INK4a should be stored at 4[o]C between 2-7 days and for future use below -18[o]C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Datenblatt des Herstellers:1.jpg