JNK2/SAPK1 Recombinant Protein
Produktgrößen
5 µg
£528,00
32-3038-5UG
Über dieses Produkt
- SKU:
- 32-3038
- Zusätzliche Namen:
- Mitogen-activated protein kinase 9||EC 2.7.11.24||Stress-activated protein kinase JNK2||c-Jun N-terminal kinase 2||JNK-55||JNK2||JNK2A||JNK2B||PRKM9||JNK2BETA||p54aSAPK||JNK2ALPHA||MAPK9||SAPK1.
- Weitere Details:
- Source : Escherichia Coli. SAPK1/JNK2 Human Recombinant (stress-activated protein kinase/c-jun kinase) is a non-glycosilated polypeptide having a molecular mass of 49.5 kDa. SAPK1/JNK2 is purified by proprietary chromatographic techniques. JUN N-terminal Kinase 2is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals; and are involved in a wide variety of cellular processes such as proliferation; differentiation; transcription regulation and development. This kinase targets specific transcription factors; and thus mediates immediate-early gene expression in response to various cell stimuli. It is most closely related to MAPK8; both of which are involved in UV radiation induced apoptosis; thought to be related to the cytochrome c-mediated cell death pathway. This gene and MAPK8 are also known as c-Jun N-terminal kinases. This kinase blocks the ubiquitination of tumor suppressor p53; and thus it increases the stability of p53 in nonstressed cells. Studies of this gene's mouse counterpart suggest a key role in T-cell differentiation. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.
- Aufreinigung:
- Greater than 95% as determined by SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. Avoid multiple freeze-thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Datenblatt des Herstellers:1.jpg