ErbB3 Recombinant Protein
Produktgrößen
20 µg
£528,00
32-3005-20UG
Über dieses Produkt
- SKU:
- 32-3005
- Zusätzliche Namen:
- Receptor tyrosine-protein kinase erbB-3||EC 2.7.10.1||c-erbB3||Tyrosine kinase-type cell surface receptor HER3||ErbB3||HER3.
- Weitere Details:
- Source : Escherichia Coli. Tyrosine Kinase ErbB3 Human Recombinant (HER3) produced in E.Coli is a single; non-glycosylated polypeptide consisting of several epitopes of extracellular domain of human Erb-b3; and having a total molecular mass of approximately 12.0 kDa.The ErbB3 is purified by proprietary chromatographic techniques. ErbB3; also called Her3 (human epidermal growth factor receptor 3); is a type I membrane glycoprotein that is a member of the ErbB family of tyrosine kinase receptors. ErbB family members serve as receptors for the epidermal growth factor (EGF) family of growth factors. Among ErbB family members; ErbB3 is unique in that it contains a defective kinase domain. ErbB3 is expressed in keratinocytes; melanocytes; skeletal muscle cells; embryonic myoblasts and Schwann cells. Monomeric ErbB3 serves as a low affinity receptor for the heregulins (HRG). ErbB3 can induce specific antibody production in vivo; hence to inhibit tumor cell growth. ErbB-3 can be used to treat early; medium and advanced or post-operative breast cancer with over-expression of ErbB2. According to its mechanism of action; ErbB3 is classified as a therapeutic for cancer.
- Aufreinigung:
- Greater than 95.0% as determined by:(a) Analysis by RP-HPLC.(b) Analysis by SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- ErbB3 although stable at 4[o]C for 1 week; should be stored below -18[o]C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Datenblatt des Herstellers:1.jpg