ErbB2 Recombinant Protein
Produktgrößen
20 µg
£528,00
32-3004-20UG
Über dieses Produkt
- SKU:
- 32-3004
- Zusätzliche Namen:
- NEU||NGL||HER2||TKR1||HER-2||c-erb B2||HER-2/neu||Receptor tyrosine-protein kinase erbB-2||EC 2.7.10.1||p185erbB2||C-erbB-2||NEU proto-oncogene||Tyrosine kinase-type cell surface receptor HER2||MLN 19||CD340 antigen.
- Weitere Details:
- Source : Escherichia Coli. ErbB-2 Human Recombinant is a 43.4 kDa protein containing 397 amino acid residues of the human Herstatin; and an extra Methionine at N-Terminal ; produced in E.coli. HER-2/neu (erbB-2) encodes an 185-kDa orphan receptor tyrosine kinase that is constitutively active as a dimer and displays potent oncogenic activity when overexpressed. Herstatin; as the product of alternative HER-2 transcript; retains intron 8.The herstatin mRNA is expressed in normal human fetal kidney and liver; but is at reduced levels relative to p185HER-2 mRNA in carcinoma cells that contain an amplified HER-2 gene. Herstatin appears to be an inhibitor of p185HER-2; because it disrupts dimers; reduces tyrosine phosphorylation of p185; and inhibits the anchorage-independent growth of transformed cells that overexpress HER-2.
- Aufreinigung:
- Greater than 95% as determined by densitometric image analysis.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Datenblatt des Herstellers:1.jpg