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YOD1 Recombinant Protein

Produktgrößen
10 µg
£528,00
32-2933-10UG
Über dieses Produkt
SKU:
32-2933
Zusätzliche Namen:
DUBA8||OTUD2||PRO0907||RP11-164O23.1||Ubiquitin thioesterase OTU1||DUBA-8||HIN-7||HsHIN7||OTU domain-containing protein 2.
Weitere Details:
Source : Escherichia Coli. YOD1 Human Recombinant produced in E.coli is a single; non-glycosylated polypeptide chain containing 371 amino acids (1-348) and having a molecular mass of 40.7kDa.YOD1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. YOD1 is a Hydrolase which removes conjugated ubiquitin from proteins and takes part in endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. YOD1 is a highly conserved deubiquitinating enzyme belonging to the ovarian tumor (otubain) family; whose function has yet to be determined in mammalian cells. YOD1 is a component of a multiprotein complex with p97 as its nucleus; proposing a functional link to a pathway responsible for the dislocation of misfolded proteins from the endoplasmic reticulum. YOD1 variant xpression deprived of its deubiquitinating activity compels a halt on the dislocation reaction; as concluded by the stabilization of various dislocation substrates.
Aufreinigung:
Greater than 90.0% as determined by SDS-PAGE.
Versandbedingungen:
Blue Ice
Lagerbedingungen:
Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Hersteller:
Abeomics
Typ:
Proteins, Peptides, Small Molecules & Other Biomolecules
  • Datenblatt des Herstellers:1.jpg