UBA3 Recombinant Protein
Produktgrößen
20 µg
£528,00
32-2877-20UG
Über dieses Produkt
- SKU:
- 32-2877
- Zusätzliche Namen:
- NEDD8-activating enzyme E1 catalytic subunit||NEDD8-activating enzyme E1C||Ubiquitin-activating enzyme E1C||Ubiquitin-like modifier-activating enzyme 3||Ubiquitin-activating enzyme 3||UBA3||UBE1C||hUBA3.
- Weitere Details:
- Source : Escherichia Coli. UBA3 Human Recombinant produced in E.coli is a single; non-glycosylated polypeptide chain containing 487 amino acids (1-463) and having a molecular mass of 54.4kDa.UBA3 is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. NEDD8-activating enzyme E1 catalytic subunit (UBA3) is the catalytic subunit of the dimeric UBA3-NAE1 E1 enzyme; which belongs to the E1 ubiquitin-activating enzyme family. E1 activates NEDD8 by initially adenylating its C-terminal glycine residue with ATP; afterwards linking this residue to the side chain of the catalytic cysteine; generating a NEDD8-UBA3 thioester and free AMP. E1 at last transfers NEDD8 to the catalytic cysteine of UBE2M. The UBA3 enzyme connects with AppBp1; an amyloid beta precursor protein binding protein; to form a heterodimer; and at that point the enzyme complex activates NEDD8; a ubiquitin-like protein; which controls cell division; signaling and embryogenesis.
- Aufreinigung:
- Greater than 90.0% as determined by SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Datenblatt des Herstellers:1.jpg