SULT1E1 Recombinant Protein
Produktgrößen
25 µg
£528,00
32-2829-25UG
Über dieses Produkt
- SKU:
- 32-2829
- Zusätzliche Namen:
- EST||STE||EST-1||MGC34459||SULT1E1||Estrogen sulfotransferase||Sulfotransferase estrogen-preferring.
- Weitere Details:
- Source : Escherichia Coli. Recombinant Human SULT1E1 produced in E.Coli is a single; non-glycosylated polypeptide chain containing 302 amino acids (1-294 a.a.) and having a molecular mass of 36.1 kDa. SULT1E1 is fused to 6 amino acid His Tag at C-terminus and purified by conventional chromatography techniques. SULT1E1 catalyzes the sulfate conjugation of many hormones; neurotransmitters; drugs; and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. SULTIE1 control the level of the estrogen receptor by sulfurylating free estradiol. maximally sulfates beta-estradiol and estrone at concentrations of 20nm. SULTIE1 in addition sulfates dehydroepiandrosterone; pregnenolone; ethinylestradiol; equalenin; diethylstilbesterol and 1-naphthol; at considerably higher concentrations; though; cortisol; testosterone and dopamine are not sulfated. Decreased SULT1E1 expression is linked with estrogen-dependent endometrial carcinomas. Altered cellular proliferation was detected in cells stably expressing SULT1E1.
- Aufreinigung:
- Greater than 95.0% as determined by SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Datenblatt des Herstellers:1.jpg