PPM1G; 546 a.a. Recombinant Protein
Produktgrößen
10 µg
£528,00
32-2714-10UG
Über dieses Produkt
- SKU:
- 32-2714
- Zusätzliche Namen:
- Protein Phosphatase 1G||PP2CG||PPP2CG||MGC1675||MGC2870||PP2C GAMMA||EC 3.1.3.16||Protein phosphatase 2C isoform gamma||PP2C-gamma||Protein phosphatase magnesium-dependent 1 gamma||Protein phosphatase 1C||PPM1G||PPM1C.
- Weitere Details:
- Source : E.coli. PPM1G Human Recombinant produced in E.coli is a single; non-glycosylated polypeptide chain containing 566 amino acids (1-546) and having a molecular mass of 61.4 kDa. The PPM1G is fused to a 20 amino acid His-Tag at N-terminus and purified by proprietary chromatographic techniques. PPM1G is part of the PP2C family of Ser/Thr protein phosphatases which are known to be negative regulators of cell stress response pathways. PPM1G is accountable for the dephosphorylation of Pre-mRNA splicing factors; an important factor for the formation of functional spliceosome. PPM1G regulates cell cycle progression. PPM1G mediates histone dephosphorylation/exchange in response to DNA damage or checkpoint recovery in higher eukaryotes. The degradation of p21/WAF1 induced by PPM1G is mediated in a proteasome-dependent manner. Protein phosphatase 1G regulates assembly and function of the beta-catenin degradation complex.
- Aufreinigung:
- Greater than 85% as determined by SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Datenblatt des Herstellers:1.jpg