PLA2G7 HEK Recombinant Protein
Produktgrößen
20 µg
£528,00
32-2684-20UG
Über dieses Produkt
- SKU:
- 32-2684
- Zusätzliche Namen:
- Platelet-activating factor acetylhydrolase||PAF acetylhydrolase||PAF 2-acylhydrolase||LDL-associated phospholipase A2||LDL-PLA(2)||2-acetyl-1-alkylglycerophosphocholine esterase||1-alkyl-2-acetylglycerophosphocholine esterase||PLA2G7||PAFAH||LP-PLA2;
- Weitere Details:
- Source : HEK293 cells. Recombinant Human PLA2G7 produced in HEK293 cells is a polypeptide chain (22-441 a.a); fused to an 8 amino acid His-tag at C-terminus; containing a total of 428 amino acids. PLA2G7 is purified by proprietary chromatographic techniques. PLA2G7 is a secreted enzyme which catalyzes the degradation of platelet-activating factor to biologically inactive products. The PLA2G7 enzyme is produced by inflammatory cells and hydrolyzes oxidised phospholipids in LDL. In the blood; PLA2G7 goes mainly with LDL and less than 20% is coupled with HDL. PLA2G7 is implicated in the development of atherosclerosis and is also a marker for cardiac disease. PLA2G7 might have a major physiologic effect in the presence of inflammatory bodily responses.PLA2G7 alters the action of PAF (platelet-activating factor) by hydrolyzing the sn-2 ester bond to yield the biologically inactive lyso-PAF. PLA2G7 has specificity for substrates with a short residue at the sn-2 position. PLA2G7 is inactive against long-chain phospholipids.PLA2G7 gene defects are the source of platelet-activating factor acetylhydrolase deficiency; which is a trait that is present in 27% of the Japanese population.
- Aufreinigung:
- Greater than 95% as determined by SEC-HPLC and SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time.Avoid multiple freeze-thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Datenblatt des Herstellers:1.jpg