PLA2G1B Recombinant Protein
Produktgrößen
10 µg
£458,00
32-2678-10UG
Über dieses Produkt
- SKU:
- 32-2678
- Zusätzliche Namen:
- Phospholipase A2||EC 3.1.1.4||Phosphatidylcholine 2-acylhydrolase||Group IB phospholipase A2||PLA2||PLA2A||PPLA2||sPLA2-IB;MGC119834||MGC119835||PLA2G1B.
- Weitere Details:
- Source : Escherichia Coli. Secreted Phospholipase A2-IB Human Recombinant is manufactured with N-terminal fusionf HisTag. PLA2G1B His-Tagged Fusion Protein is 16 kDa containing 126 amino acid residues of the human secreted phospholipase A2-IB and 16 additional amino acid residues - HisTag .MRGSHHHHHH GMASHMAVWQ FRKMIKCVIP GSDPFLEYNN YGCYCGLGGS GTPVDELDKC CQTHDNCYDQ AKKLDSCKFL LDNPYTHTYS YSCSGSAITC SSKNKECEAF ICNCDRNAAI CFSKAPYNKA HKNLDTKKYC QS. Group IB secretory phospholipase A2 (sPLA2-IB) mediates cell proliferation; cell migration; hormone release and eicosanoid production via its receptor in peripheral tissues. In the CNS; high-affinity binding sites of sPLA2-IB have been documented. sPLA2-IB induced neuronal cell death in a concentrationdependent manner depending on PGD2 metabolites; especially Delta12-PGJ2 that might mediate sPLA2-IB-induced apoptosis. The secretory PLA2 (sPLA2) family; in which 10 isozymes have been identified; consists of lowmolecular weight; Ca2+-requiring secretory enzymes that have been implicated in a number of biological processes; such as modification of eicosanoid generation; inflammation; and host defense.
- Aufreinigung:
- Greater than 95% as determined by SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store protein at -20[o]C. Aliquot the product to avoid repeated freezing/thawing cycles. Protein can be stored at 4[o]C for a limited period of time.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Datenblatt des Herstellers:1.jpg