MMP 1 HEK Recombinant Protein
Produktgrößen
10 µg
£528,00
32-2543-10UG
Über dieses Produkt
- SKU:
- 32-2543
- Zusätzliche Namen:
- Interstitial collagenase||Fibroblast collagenase||Matrix metalloproteinase-1||MMP-1||MMP1||CLG||CLGN.
- Weitere Details:
- Source : HEK293 cells. MMP-1 Human Recombinant produced in HEK293 cells is a proform of the Human MMP1 (Met1-Asn469) and fused with a ployhistide tag at the C-terminus; having an Mw of 52kDa. MMP-1 is purified by proprietary chromatographic techniques. MMP-1 (interstitial collagenase) can break down a wide range of substrates including types I; II; III; VII; VIII; and X collagens as well as L-Selectin; pro-TNF; IL-1; IGFBP-3; IGFBP-5; casein; gelatin; ?1 antitrypsin; myelin basic protein; pro-MMP2 and pro-MMP9. A significant function of MMP-1 is the degradation of fibrillar collagens in extracellular matrix remodeling. MMP-1 is expressed in fibroblasts; keratinocytes; endothelial cells; monocytes and macrophages. MMP1 can be divided into a number of distinct domains: a prodomain which is cleaved on activation; a catalytic domain containing the zinc binding site and a short hinge region with a carboxyl terminal domain. MMP1 is part of a cluster of MMP genes which localize to chromosome 11q22.3.
- Aufreinigung:
- Greater than 95% as determined by SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time.Avoid multiple freeze-thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Assay Kits:MMP
- Datenblatt des Herstellers:1.jpg