HAAO Recombinant Protein
Produktgrößen
10 µg
£528,00
32-2422-10UG
Über dieses Produkt
- SKU:
- 32-2422
- Zusätzliche Namen:
- 3-hydroxyanthranilate 3;4-dioxygenase||3-hydroxyanthranilate oxygenase||3-HAO||3-hydroxyanthranilic acid dioxygenase||HAD||HAAO||HAO.
- Weitere Details:
- Source : Escherichia Coli. HAAO Human Recombinant produced in E.Coli is a single; non-glycosylated polypeptide chain containing 310 amino acids (1-286 a.a.) and having a molecular mass of 35kDa.HAAO is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. HAAO is a monomeric cytosolic protein which is a member of intramolecular dioxygenases family containing nonheme ferrous iron. The HAAO protein catalyzes the synthesis of quinolinic acid (QUIN) from 3-hydroxyanthranilic acid. QUIN is an excitotoxin whose toxicity is facilitated by its ability to activate glutamate N-methyl-D-aspartate receptors. Amplified cerebral levels of QUIN may contribute to the pathogenesis of neurologic and inflammatory disorders. HAAO is widely distributed in peripheral organs; such as liver and kidney; and is also present in low amounts in the central nervous system.
- Aufreinigung:
- Greater than 90.0% as determined by SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Datenblatt des Herstellers:1.jpg