GPX1 Recombinant Protein
Produktgrößen
20 µg
£528,00
32-2393-20UG
Über dieses Produkt
- SKU:
- 32-2393
- Zusätzliche Namen:
- Glutathione peroxidase 1||GPx-1||GSHPx-1||Cellular glutathione peroxidase||GPX1||GPXD||GSHPX1.
- Weitere Details:
- Source : Escherichia Coli. GPX1 Human Recombinant produced in E.coli is a single; non-glycosylated polypeptide chain containing 223 amino acids (1-203) and having a molecular mass of 24.2kDa.GPX1 is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Glutathione peroxidase 1 (GPX1) is a member of the glutathione peroxidase family; consisting of 8 identified glutathione peroxidases (Gpx1-8) in humans. Glutathione peroxidase serves in the detoxification of hydrogen peroxide; and is one of the most vital antioxidant enzymes in humans. The GPX1 is a component of the enzymatic antioxidant defense; preventing oxidative damage to DNA; proteins and lipids by detoxifying hydrogen and lipid peroxides which may contribute to prostate cancer development. GPX1 is one of only a small number of proteins known in higher vertebrates to contain selenocysteine; which occurs at the active site of glutathione peroxidase and is coded by the nonsense (stop) codon TGA. Furthermore; the GPX1 protein is characterized in a polyalanine sequence polymorphism in the N-terminal region; which includes 3 alleles with 5; 6 or 7 alanine (ALA) repeats in this sequence. The allele with 5 ALA repeats is significantly linked to breast cancer risk.
- Aufreinigung:
- Greater than 90% as determined by SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Datenblatt des Herstellers:1.jpg