Fumarase Recombinant Protein
Produktgrößen
50 µg
£528,00
32-2333-50UG
Über dieses Produkt
- SKU:
- 32-2333
- Zusätzliche Namen:
- MCL||LRCC||HLRCC||MCUL1||FH||Fumarate hydratase||Fumarase.
- Weitere Details:
- Source : Escherichia Coli. Fumarase Human Recombinant produced in E.Coli is a single; non-glycosylated polypeptide chain containing 467 amino acids (44-510) and having a molecular mass of 50.2 kDa. Fumarate Hydratase is purified by proprietary chromatographic techniques. Fumarase is an enzymatic factor of Krebs cycle; which catalyzes the formation of L-malate from fumarate. Fumarase exists in both a cytosolic form and an N-terminal extended form; differing only in the translation start site used. The N-terminal extended form is aimed to the mitochondrion; where the removal of the extension results in the same form as in the cytoplasm. Fumarase is similar to a number of thermostable Class-2 fumarases and functions as a homotetramer. Mutations in the Fumarase gene causes fumarase deficiency and leads to progressive encephalopathy; cerebral atrophy and developmental delay. Fumarase enzyme is also thought to act as a tumor suppressor. Leydig cell tumors are caused by Fumarase mutations and represents one of the first reports of germline mutations in any type of adult testicular tumor.
- Aufreinigung:
- Greater than 95.0% as determined by SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Datenblatt des Herstellers:1.jpg