FTCD Recombinant Protein
Produktgrößen
10 µg
£452,00
32-2331-10UG
Über dieses Produkt
- SKU:
- 32-2331
- Zusätzliche Namen:
- Formiminotransferase-cyclodeaminase||FTCD||LCHC1||LC-1.
- Weitere Details:
- Source : Sf9 insect cells. Formiminotransferase Cyclodeaminase Human Recombinant (also called liver cytosol type 1) produced in SF9; is a glycosylated; polypeptide chain having a molecular mass of 59;749 Dalton.The FTCD is expressed with a -6xHis tag and purified by proprietary chromatographic techniques. Formiminotransferase cyclodeaminase is an enzyme which catalyzes the conversion of formiminoglutamateand tetrahydrofolateinto formiminotetrahydrofolateand glutamate.Formiminotransferase cyclodeaminase; a bifunctional enzyme of tetrahydrofolate synthesis; is the target antigen of anti-LC1 (liver cytosol antigen type 1) autoantibodies. Presence of LC1 autoantibodies is a marker for type 2 autoimmune hepatitis (for which anti-LKM 1/cytochrome P450 2D6 autoantibodies are a further marker).Serum LC1 autoantibody concentrations appear to fluctuate in parallel with aminotransferase levels; a particularly intriguing observation that suggests a possible role of LC1 autoreactivity in the pathogenic mechanism leading to hepatocyte injury.
- Aufreinigung:
- Greater than 95% as determined by SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]Cfor longer periods of time. Avoid multiple freeze-thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Datenblatt des Herstellers:1.jpg