Dopa Decarboxylase Recombinant Protein
Produktgrößen
20 µg
£528,00
32-2280-20UG
Über dieses Produkt
- SKU:
- 32-2280
- Zusätzliche Namen:
- DDC||AADC||Aromatic-L-amino-acid decarboxylase||DOPA decarboxylase.
- Weitere Details:
- Source : Escherichia Coli. Dopa decarboxylase human recombinant produced in E.Coli is a single; non-glycosylated; polypeptide chain containing 503 amino acids (1-480 a.a.) and having a molecular mass of 56.4 kDa. The Dopa decarboxylase is fused to 23 amino acid His Tag at N-terminus and purified by conventional chromatpgraphy. Dopa decarboxylase is a homodimeric; pyridoxal phosphate dependent enzyme. Dopa decarboxylase is involved in 2 metabolic pathways; synthesizing 2 significant neurotransmitters: dopamine and serotonin which both take part in numerous clinical disorders; including Parkinson's disease. Dopa decarboxylase is located in different areas of the brain and is mostly found in basal ganglia. Dopa decarboxylase catalyzes the decarboxylation of L-3;4-dihydroxyphenylalanine (DOPA) to dopamine; L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine. Defects in Dopa decarboxylase leads to aromatic L-amino-acid decarboxylase deficiency (AADCD). AADCD deficiency is an inborn error in neurotransmitter metabolism that causes combined serotonin and catecholamine deficiency.
- Aufreinigung:
- Greater than 95.0% as determined by SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Datenblatt des Herstellers:1.jpg