DAAO Recombinant Protein
Produktgrößen
10 µg
£528,00
32-2254-10UG
Über dieses Produkt
- SKU:
- 32-2254
- Zusätzliche Namen:
- D-amino-acid oxidase||DAMOX||DAAO||DAO||OXDA||MGC35381.
- Weitere Details:
- Source : Escherichia Coli. DAAO Human Recombinant fused with 20 amino acid His tag at N-terminus produced in E.Coli is a single; non-glycosylated; polypeptide chain containing 367 amino acids (1-347 a.a.) and having a molecular mass of 41.6kDa.The DAAO is purified by proprietary chromatographic techniques. DAAO is a peroxisomal enzyme which uses FAD (flavin adenine dinucleotide) as a cofactor and oxidizes D-amino acids to the corresponding amino acids; producing ammonia and hydrogen peroxide. DAAO substrates include an extensive array of D-amino acids; but it is inactive on the naturally occurring L-amino acids. DAAO acts on a variety of D-amino acids especially on those having small hydrophobic side chains followed by those bearing polar; aromatic; and basic groups; however it doesn't act on acidic amino acids. DAAO may be involved in acid base balance in the kidney or it could act as a detoxifying agent which removes D-amino acids accumulated during aging. DAAO regulates the neuromodulator D-serine level in the brain. DAAO is highly active towards D-DOPA and contributes to dopamine synthesis. Creatinine inhibits the DAAO in uremia. DAAO may also have a role in the pathophysiology of schizophrenia; but not in bipolar disorder.
- Aufreinigung:
- Greater than 95.0% as determined by SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Datenblatt des Herstellers:1.jpg