COMT Recombinant Protein
Produktgrößen
10 µg
£528,00
32-2225-10UG
Über dieses Produkt
- SKU:
- 32-2225
- Zusätzliche Namen:
- COMT||EC 2.1.1.6||Catechol O-methyltransferase.
- Weitere Details:
- Source : Escherichia Coli. COMT Human Recombinant produced in E.Coli is a single; non-glycosylated polypeptide chain containing 221 amino acids (51-271 a.a.) & having a molecular mass of 24.4 kDa. The COMT is purified by proprietary chromatographic techniques. COMT catalyzes the transfer of a methyl group from S-adenosylmethionine (SAM) to catechol substrates such as the neurotransmitters dopamine; epinephrine; and norepinephrine. This O-methylation results in one of the main degradative pathways of the catecholamine transmitters. COMT COMT is located in the postsynaptic neuron and is involved in the metabolism of catechol estrogen drugs used in the treatment of hypertension; asthma; Parkinson disease and the inactivation of catecholamine neurotransmitters though enzymatic degradation. COMT appears in tissues in 2 forms; a soluble form and a membrane-bound form which differ in their N-termini. COMT inhibitors prevent levodopa degradation; increase its availability and are used in the treatment of patients with Parkinson's disease.
- Aufreinigung:
- Greater than 95.0% as determined by SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Datenblatt des Herstellers:1.jpg