CBR3 Recombinant Protein
Produktgrößen
20 µg
£528,00
32-2211-20UG
Über dieses Produkt
- SKU:
- 32-2211
- Zusätzliche Namen:
- Carbonyl reductase [NADPH] 3||NADPH-dependent carbonyl reductase 3||CBR3||carbonyl reductase 3||hCBR3||SDR21C2.
- Weitere Details:
- Source : Escherichia Coli. Recombinant Human CBR3 fused with a 20 amino acid His tag at N-terminus produced in E.Coli is a single; non-glycosylated polypeptide chain containing 297 amino acids (1-277 a.a) and having a molecular mass of 33kDa. CBR3 is purified by proprietary chromatographic techniques. CBR3 catalyzes the reduction of a large number of biologically and pharmacologically active carbonyl compounds to their corresponding alcohols. CBR3 is one of several monomeric NADPH-dependent oxidoreductases. Furthermore; CBR3 contains 3 exons spanning 11.2 kilobases and is strongly linked to another carbonyl reductase gene; the CBR1. It was suggested that CBR3 mediates 9-cis-retinoic acid-induced cytostatis and is a potential prognostic marker for oral malignancy.CBR3 is identified in the ovary; pancreas; intestine; colon; kidney; brain; thymus; lung; heart; liver; spleen; leukocyte; prostate and the testis.Polymorphisms in CBR3 may give an explanation to interindividual and interethnic variability of doxorubicin pharmacokinetics and pharmacodynamics.
- Aufreinigung:
- Greater than 95.0% as determined by analysis by SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Datenblatt des Herstellers:1.jpg