BLVRA Recombinant Protein
Produktgrößen
50 µg
£528,00
32-2190-50UG
Über dieses Produkt
- SKU:
- 32-2190
- Zusätzliche Namen:
- Biliverdin reductase A||BVR A||Biliverdin-IX alpha-reductase||BLVRA||BLVR||BVR||BVRA.
- Weitere Details:
- Source : Escherichia Coli. BLVRA Human Recombinant produced in E.Coli is a single; non-glycosylated; polypeptide chain containing 295 amino acids (3-296 a.a. and Methionine at N-terminus) and having a molecular mass of 33.3kDa (molecular weight on SDS-PAGE will shift up).The BLVRA is purified by proprietary chromatographic techniques. Biliverdin reductase A (BLVRA) is a member of the gfo/idh/mocA family. BLVRA is an enzyme that converts biliverdin to bilirubin; converting a double-bond between the second and third pyrrole ring into a single-bond. BLVRA reduces the gamma-methene bridge of the open tetrapyrrole; biliverdin IX alpha; to bilirubin with the simultaneous oxidation of a NADH or NADPH cofactor (Bilirubin + NAD(P)+ = biliverdin + NAD(P)H ).BLVRA is a regulator for induction of activating transcription factor-2 and heme oxygenase-1. Furthermore; BLVRA enhances the role of HO-1 in cytoprotection and provides cytoprotection independent of heme degradation. In addition; Bilirubin while acting as a cytoprotective antioxidant is itself oxidized to biliverdin and subsequently recycled by biliverdin reductase back to bilirubin.
- Aufreinigung:
- Greater than 90.0% as determined by SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Datenblatt des Herstellers:1.jpg