AUH Recombinant Protein
Produktgrößen
20 µg
£528,00
32-2173-20UG
Über dieses Produkt
- SKU:
- 32-2173
- Zusätzliche Namen:
- Methylglutaconyl-CoA hydratase||mitochondrial||AU-specific RNA-binding enoyl-CoA hydratase||AU-binding protein/enoyl-CoA hydratase||AUH.
- Weitere Details:
- Source : Escherichia Coli. AUH Human Recombinant fused with a 21 amino acid His tag at N-terminus produced in E.Coli is a single; non-glycosylated; polypeptide chain containing 293 amino acids (68-339 a.a.) and having a molecular mass of 31.4kDa. The AUH is purified by proprietary chromatographic techniques. Mitochondrial methylglutaconyl-CoA hydratase (AUH) is involved in the amino acid degradation pathway by catalyzing the conversion of 3-methylglutaconyl-CoA to 3-hydroxy-3-methylglutaryl-CoA and water. AUH Human is expressed as a single mRNA species of 1.8 kb; and translated as a 40kDa precursor protein which is consequently processed to a 32kDa mature form. AUH has a very low enoyl-CoA hydratase activity. The AUH protein binds to the AU-rich element (ARE); which is a common element found in the 3' UTR of rapidly decaying mRNA such as c-fos; c-myc and granulocyte/ macrophage colony stimulating factor. AU-rich elements are involved in directing RNA to rapid degradation and deadenylation. In addition; AUH is homologous to enol-CoA hydratase; which is an enzyme involved in fatty acid degradation; and has been shown to have intrinsic hydratase enzymatic activity. AUH is therefore a bifunctional chimera between RNA binding and metabolic enzyme activity.
- Aufreinigung:
- Greater than 95.0% as determined by SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- AUH should be stored desiccated below -18[o]C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Datenblatt des Herstellers:1.jpg