MIP 3 Alpha His Recombinant Protein
Produktgrößen
10 µg
£528,00
32-1969-10UG
Über dieses Produkt
- SKU:
- 32-1969
- Zusätzliche Namen:
- S Small inducible cytokine A20 precursor||CCL20||Macrophage inflammatory protein 3 alpha||MIP-3-alpha||Liver and activation- regulated chemokine||CC chemokine LARC||Beta chemokine exodus-1||CKb4||LARC||ST38||MIP3A||MIP-3a||SCYA20.
- Weitere Details:
- Source : Escherichia Coli. MIP 3a Human Recombinant fused with a 21 amino acid His tag at N-terminus produced in E.Coli is a single; non-glycosylated; polypeptide chain containing 91 amino acids (27-96 a.a.) and having a molecular mass of 10.3kDa. The MIP 3a is purified by proprietary chromatographic techniques. CCL-20 is a chemotactic factor that draws lymphocytes & neutrophils; rathar than monocytes. MIP-3 alpha inhibits proliferation of myeloid progenitors in colony formation assays. MIP3A plays a role in the formation and function of the mucosal lymphoid tissues by attracting lymphocytes and dendritic cells towards epithelial cells. C-terminal processed forms have been shown to be equally chemotactically active for leukocytes. CCL-20 holdes antibacterial activity e.coli atcc 25922 and s.aureus atcc 29213. CCL-20 gene transcription is activated by H. pylori; which activates NF-kappaB through intracellular signal pathway which involves IkappaB kinase and NF-kappaB-inducing kinase. MIP-3 alpha is invloved in chemokine-mediated lymphocyte trafficking during gastric inflammation in Helicobacter infection. CCL-20 expression is involved in the recruitment of CD45R0-positive T cell subsets into the intestinal lamina propria. MIP-3A is in charge of the advancement of pulpal inflammation through the recruitment of C-C motif Receptor 6-expressing lymphocytes Vaginal epithelial cells respond to factors present in semen by secreting MIP-3 alpha; which increases langerhans cells recruitment during HIV transmission.
- Aufreinigung:
- Greater than 85.0% as determined by SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Datenblatt des Herstellers:1.jpg