IL-10 (human):Fc (human) (Recombinant) (non-lytic)
Produktgrößen
10 µg
£546,00
32-190045-10UG
50 µg
£709,00
32-190045-50UG
Über dieses Produkt
- SKU:
- 32-190045
- Zusätzliche Namen:
- Interleukin-10; Cytokine Sythesis Inhibitory Factor; CSIF
- Weitere Details:
- Source :CHO cells Specific Interleukin-10 (IL-10) is a cytokine produced by activated Th2 cells; B cells; keratinocytes and monocytes/macrophages. In vitro murine and human IL-10 inhibits cytokine synthesis by Th1 cells; natural killer cells and monocytes/macrophages. Several studies have suggest the potential application of IL-10 as an anti-inflammatory agent in the treatment of septic shock and as an immunosuppressive agent in certain T cell mediated autoimmune diseases.Other Product Data Non-lytic: Acts as a long lasting fusion protein which only binds to the receptor. Mutations to the complement (C1q) and FcgR I binding sites of the IgGs Fc fragment render the fusion proteins incapable of antibody directed cytotoxicity (ADCC) and complement directed cytotoxicity (CDC).
- Aufreinigung:
- >=98% (SDS-PAGE)
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Short Term Storage +4[o]C ; Long Term Storage-20[o]C ; Avoid freeze/thaw cycles. Stable for at least 1 year after receipt when stored at -20[o]C. Working aliquots are stable for up to 3 months when stored at -20[o]C.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Datenblatt des Herstellers:32-190045 proliferation assay.jpg