CCL16 Recombinant Protein
Produktgrößen
20 µg
£528,00
32-1861-20UG
Über dieses Produkt
- SKU:
- 32-1861
- Zusätzliche Namen:
- C-C motif chemokine 16||Small-inducible cytokine A16||IL-10-inducible chemokine||Chemokine LEC||Monotactin-1||Chemokine CC-4||Lymphocyte and monocyte chemoattractant||CCL-16||HCC-4||HCC4||NCC4||NCC-4||Liver Expressed Chemokine||LMC||LCC-1||LCC1||MTN-
- Weitere Details:
- Source : Escherichia Coli. CCL16 Human Recombinant produced in E.Coli is a non-glycosylated; Polypeptide chain containing 97 amino acids and having a molecular mass of 11.2 kDa. The CCL16 is purified by proprietary chromatographic techniques. Human CCL16; also called HCC-4; liver-expressed chemokine (LEC); and lymphocyte and monocyte chemoattractant (LMC); is a novel CC chemokine recognized by bioinformatics. NCC-4 cDNA encodes a 120 amino acids along with a 23 amino acids signal peptide that is cleaved to generate 97 amino acid protein. HCC4 is vaguely related to other CC chemokines; showing less than 30% sequence identity. Among CC chemokines; CCL-16 has the largest similarity to HCC-1. 2 potential polyadenylation signals are present on the human HCC-4 gene; and as a result; 2 transcripts containing roughly 1;500 base pairs and 500 base pairs have been detected. HCC-4 is expressed weakly by some lymphocytes; including NK cells; T cells; and some T cell clones. The expression of HCC-4 in monocytes is greatly upregulated in the presence of IL-10. CCL16 shows chemotactic activity for lymphocytes and monocytes rather than to neutrophils. NCC-4 has potent myelosuppressive activity; suppresses proliferation of myeloid progenitor cells. CCL16 demonstrates chemotactic activity for monocytes and thp-1 monocytes; rather than for resting lymphocytes and neutrophils. HCC-4 induces a calcium flux in thp-1 cells that desensitized prior to the expression of rantes.
- Aufreinigung:
- Greater than 97.0% as determined by:(a) Analysis by RP-HPLC.(b) Analysis by SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Lyophilized CCL16 although stable at room temperature for 3 weeks; should be stored desiccated below -18[o]C. Upon reconstitution CCL16 should be stored at 4[o]C between 2-7 days and for future use below -18[o]C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Datenblatt des Herstellers:1.jpg