rVEGFC Recombinant Protein
Produktgrößen
10 µg
£528,00
32-1843-10UG
Über dieses Produkt
- SKU:
- 32-1843
- Zusätzliche Namen:
- VEGF-C||Vascular endothelial growth factor C||VRP||Flt4 ligand||Flt4-L.
- Weitere Details:
- Source : Sf9; Insect Cells. Vascular Endothelial Growth Factor C Rat Recombinant contains 129 amino acids residues and was fused to a His- tag (6x His) at the C-terminal end. As a result of glycosylation VEGF-C migrates as an 18-24 kDa protein in SDS-PAGE under reducing conditions. VEGF-C; also known as Vascular Endothelial Growth Factor Related Protein (VRP); is a recently discovered VEGF growth factor family member that is most closely related to VEGF-D. The rat VEGFC cDNA encodes a pre-pro-protein of 416 amino acids residues. It is almost identical to the mouse VEGF-C protein. Similar to VEGF-D; VEGF-C has a VEGF homology domain spanning the middle third of the precursor molecule and long N- and C-terminal extensions. In adults; VEGF-C is highly expressed in heart; placenta; ovary and small intestine. Recombinant rat VEGF-C; lacking the N- and C-terminal extensions and containing only the middle VEGF homology domain; forms primarily non-covalently linked dimers. This protein is a ligand for both VEGFR-2/KDR and VEGFR-3/FLT -4. Since VEGFR-3 is strongly expressed in lymphatic endothelial cells; it has been postulated that VEGF-C is involved in the regulation of the growth and/or differentiation of lymphatic endothelium. Although recombinant rat VEGF-C is also a mitogen for vascular endothelial cells; it is much less potent than VEGF-A.
- Aufreinigung:
- Greater than 90.0% as determined by:(a) Analysis by RP-HPLC.(b) Analysis by SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Lyophilized Vascular Endothelial Growth Factor-C although stable at room temperature for 3 weeks; should be stored desiccated below -18[o]C. Upon reconstitution VEGF-C should be stored at 4[o]C between 2-7 days and for future use below -18[o]C.Please prevent freeze-thaw cycles.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Datenblatt des Herstellers:1.jpg