TNFSF12 Recombinant Protein
Produktgrößen
25 µg
£528,00
32-1811-25UG
Über dieses Produkt
- SKU:
- 32-1811
- Zusätzliche Namen:
- TWEAK||TNF-related weak inducer of apoptosis||TNFSF12||DR3LG||Apo3-Ligand||APO3L||TNFRSF12A||Tumor necrosis factor ligand superfamily member 12||MGC20669||MGC129581.
- Weitere Details:
- Source : HEK293. The TWEAK Human Recombinant is manufactured with N-terminal fusion of 13 amino acid FLAG Tag. The TNFSF12 Flag -Tagged Fusion Protein has a Mw of 18.7kDa containing a total of 169 amino acid residues. TNFSF12 is a cytokine that is part of the TNF ligand family. TNFSF12 is a ligand for the FN14/TWEAKR receptor. TNFSF12 has overlapping signaling functions with TNF; but displays a much wider tissue distribution. TNFSF12 induces apoptosis through multiple pathways of cell death in a cell type-specific manner. TNFSF12 promotes proliferation and migration of endothelial cells; and therefore acts as a regulator of angiogenesis. TNFSF12 is expressed in adult heart; pancreas; skeletal muscle; small intestine; spleen and peripheral blood lymphocytes. TWEAK h induces NFkB and chemokine secretion. TNFSF12 exerts an apoptotic activity in HT-29 human adenocarcinoma cells whilst cultured in the presence of IFN-. TNFSF12 promotes proliferation and migration of endothelial cells.
- Aufreinigung:
- Greater than 90% as determined by SDS-PAGE.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store lyophilized TWEAK Human recombinant at -20[o]C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4[o]C for a limited period of time; it does not show any change after two weeks at 4[o]C.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Datenblatt des Herstellers:1.jpg