Recombinant Human CCL16 Protein
Produktgrößen
50 µg
£760,00
32-18091-50UG
Über dieses Produkt
- SKU:
- 32-18091
- Zusätzliche Namen:
- C-C Motif Chemokine 16; Chemokine CC-4; HCC-4; Chemokine LEC; IL-10-Inducible Chemokine; LCC-1; Liver-Expressed Chemokine; Lymphocyte and Monocyte Chemoattractant; LMC; Monotactin-1; MTN-1; NCC-4; Small-Inducible Cytokine A16; CCL16; ILINCK; NCC4; SCYA16
- Weitere Details:
- Molecular weight: 11 KDaDescription: Recombinant Human C-C Motif Chemokine 16 is produced by our E.coli expression system and the target gene encoding Gln24-Gln120 is expressed.CCL16 is a member of CC chemokine family. CCL16 cDNA encodes a 120 amino acid peptide along with a 23 amino acids signal peptide that is cleaved to generate 97 amino acid protein. CCL16 is distantly related to other CC chemokines; showing less than 30% sequence identity. CCL16 elicits its effects on cells by interacting with cell surface chemokine receptors such as CCR1; CCR2; CCR5 and CCR8. Recombinant CCL16 has been shown to chemoattract human monocytes and THP1 cells but not resting lymphocytes nor neutrophils. CCL16 has potent myelosuppressive activity; suppresses proliferation of myeloid progenitor cells. CCL16ninduces a calcium flux in THP1 cells that can be desensitized by prior exposure to RANTES; suggesting that CCL16 and RANTES share the same receptor in THP1 cells.
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Datenblatt des Herstellers:download_pdf.php