Recombinant Human IL-28A (C-6His) Protein
Produktgrößen
50 µg
£726,00
32-18086-50UG
Über dieses Produkt
- SKU:
- 32-18086
- Zusätzliche Namen:
- Interferon lambda-2; IFN-lambda-2; Cytokine Zcyto20; Interleukin-28A; IL-28A; IFNL2; IL28A; ZCYTO20
- Weitere Details:
- Molecular weight: 20.6 KDaDescription: Recombinant Human Interferon Lambda-2 is produced by our Mammalian expression system and the target gene encoding Val26-Val200 is expressed with a 6His tag at the C-terminus.IL-28A (Interferon-ÃŽ»2? IFN-ÃŽ»2); IL-28B/IFN-ÃŽ»3; and IL-29/IFN-ÃŽ»1 are type III interferons which are distantly related to IL-10 family and type I IFN family cytokines. Mature human IL-28A is an approximately 22-25 kDa protein that shares 66% amino acid (aa) sequence identity with mouse and rat IL-28A and shows cross-species activity. It shares 96% and 70% aa sequence identity with human IL-28B and IL-29; respectively. IL-28A promotes the Th1 polarization of dendritic cells in the airway and inhibits Th2 and Th17 mediated inflammation. IL-28A additionally exhibits anti-tumor activity; in part by enhancing IL-12 dependent anti-tumor CTL responses in vivo. In contrast; it is up-regulated in invasive bladder cancer where it promotes tumor cell migration.
- Host:
- HEK293
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Hersteller:
- Abeomics
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Datenblatt des Herstellers:download_pdf.php